Article
Characterization of the swine major histocompatibility complex alleles at eight loci in Westran pigs.
Xenotransplantation - 1 Jul 2005
Lee Jun-Heon, Simond Denbigh, Hawthorne Wayne J, Walters Stacey N, Patel Anita T, Smith Douglas M, O'Connell Phillip J, Moran Chris
Abstract excerpt
BACKGROUND: Pigs are an important large animal model for transplantation and a potential source of xenografts. Swine leukocyte antigen (SLA) molecules are strong mediators of alloreactive and xenoreactive immune responses. We have characterized the SLA alleles of a new pig line bred for transplantation research, the Westran (Westmead Hospital transplantation) pig, described in a companion paper. METHODS: Three...
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