Article
Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study.
Investigative ophthalmology & visual science - 9 Sept 2014
Restrepo Nicole A, Spencer Kylee L, Goodloe Robert, Garrett Tiana A, Heiss Gerardo, Bůžková Petra, Jorgensen Neal, Jensen Richard A, Matise Tara C, Hindorff Lucia A, Klein Barbara E K, Klein Ronald, Wong Tien Y, Cheng Ching-Yu, Cornes Belinda K, Tai E-Shyong, Ritchie Marylyn D, Haines Jonathan L, Crawford Dana C
Abstract excerpt
PURPOSE: Substantial progress has been made in identifying susceptibility variants for AMD in European populations; however, few studies have been conducted to understand the role these variants play in AMD risk in diverse populations. The present study aims to examine AMD risk across diverse populations in known and suspected AMD complement factor and lipid-related loci. METHODS: Targeted genotyping was...
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