Article
The role of obesity, hypertension and diet in diabetes and its complications in the Spontaneous Hypertensive/NIH-corpulent rat.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000
Michaelis O E, Carswell N, Velasquez M T, Hansen C T
Abstract excerpt
The Spontaneous Hypertensive/NIH-corpulent rat is a recently developed genetic model of obesity and diabetes. The strain exhibits both metabolic and histopathological characteristics associated with non-insulin dependent diabetes mellitus in humans. This rodent model is unique in that glucose intolerance is expressed in both sexes and in both phenotypes.
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