The role of obesity, hypertension and diet in diabetes and its complications in the Spontaneous Hypertensive/NIH-corpulent rat.

Article

The role of obesity, hypertension and diet in diabetes and its complications in the Spontaneous Hypertensive/NIH-corpulent rat.

Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000

Michaelis O E, Carswell N, Velasquez M T, Hansen C T

Abstract excerpt

The Spontaneous Hypertensive/NIH-corpulent rat is a recently developed genetic model of obesity and diabetes. The strain exhibits both metabolic and histopathological characteristics associated with non-insulin dependent diabetes mellitus in humans. This rodent model is unique in that glucose int...

Topics

Animals
Blood Glucose
Diabetes Mellitus, Experimental
Diet
Female
Genotype
Hypertension
Male
Obesity
Rats
Rats, Inbred SHR

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