Article
Molecular mimicry and immune-mediated diseases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 1998
Oldstone M B
Abstract excerpt
Molecular mimicry has been proposed as a pathogenetic mechanism for autoimmune disease, as well as a probe useful in uncovering its etiologic agents. The hypothesis is based in part on the abundant epidemiological, clinical, and experimental evidence of an association of infectious agents with au...
Topics
- Animals
- Antigens
- Autoantibodies
- Autoimmune Diseases
- Cross Reactions
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- HLA Antigens
- HLA-B27 Antigen
- Humans
- Mice
- Mice, Transgenic
- Molecular Mimicry
- Molecular Structure
- Rabbits
- T-Lymphocytes, Cytotoxic
- Virus Diseases