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Article

Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.

Investigative ophthalmology & visual science - 4 Sept 2014

Chung Duk-Won D, Frausto Ricardo F, Ann Lydia B, Jang Michelle S, Aldave Anthony J

Abstract excerpt

PURPOSE: To assess the impact of zinc finger E-box binding homeobox 1 (ZEB1) gene mutations associated with posterior polymorphous corneal dystrophy 3 (PPCD3) and Fuchs' endothelial corneal dystrophy (FECD). METHODS: Thirteen of the 27 previously reported ZEB1 truncating mutations associated with PPCD3 and the six previously reported ZEB1 missense mutations associated with FECD were generated and transiently...

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Source

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Identifiers

PMID: 25190660
DOI: 10.1167/iovs.14-15247
PMCID: PMC4184387

Genes

ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.PMID 25190660Read ↗

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