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Article

Further genetic and clinical insights of posterior polymorphous corneal dystrophy 3.

JAMA ophthalmology - 1 Oct 2013

Liskova Petra, Palos Michalis, Hardcastle Alison J, Vincent Andrea L

Abstract excerpt

IMPORTANCE: Posterior polymorphous corneal dystrophy (PPCD) is a very rare disorder characterized by primary changes of the posterior corneal layers. Sequence variants in 3 genes are associated with the development of PPCD, including ZEB1 that is responsible for PPCD3. Evidence suggests at least 1 more gene remains to be identified. OBJECTIVE: To determine the molecular genetic cause of PPCD3. DESIGN: We...

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Identifiers

PMID: 23807282
DOI: 10.1001/jamaophthalmol.2013.405

Genes

ZEB1

Variants

Provenance

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