Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy

4 Sept 2014

Abstract excerpt

A quantitative real-time PCR (qRT-PCR) assay with single-copy sensitivity targeting HIV-1 gag RNA (the gag single-copy assay [gSCA]) has been used widely to quantify plasma viremia below the limit of detection of clinical assays in patients on effective antiretroviral therapy (ART), but viral RNA in 15 to 30% of samples amplifies inefficiently because of primer/probe mismatches. We sought to develop improved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25187636
DOI: 10.1128/jcm.02060-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral TherapyPMID 25187636Read ↗

New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in PlasmaSemantic proximity Read ↗

A Simpler and More Sensitive Single-Copy HIV-1 RNA Assay for Quantification of Persistent HIV-1 Viremia in Individuals on Suppressive Antiretroviral TherapySemantic proximity Read ↗

New Tools for Quantifying HIV-1 Reservoirs: Plasma RNA Single Copy Assays and BeyondSemantic proximity Read ↗

ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy ViremiaSemantic proximity Read ↗

New Frontiers in Measuring and Characterizing the HIV ReservoirSemantic proximity Read ↗

HIV-1 low copy viral sequencing-A prototype assay.Semantic proximity Read ↗

Improved conditions for extraction and amplification of human immunodeficiency virus type 1 RNA from plasma samples with low viral load.Semantic proximity Read ↗

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNASemantic proximity Read ↗

Cross-Clade Ultrasensitive PCR-Based Assays To Measure HIV Persistence in Large-Cohort StudiesSemantic proximity Read ↗

A Robust PCR Protocol for HIV Drug Resistance Testing on Low-Level Viremia Samples.Semantic proximity Read ↗

Significance and clinical management of persistent low-level viremia and very-low-level viremia in HIV-1-infected patients.Semantic proximity Read ↗

Development of Calibrated Viral Load Standards for Group M Subtypes of Human Immunodeficiency Virus Type 1 and Performance of an Improved AMPLICOR HIV-1 MONITOR Test with Isolates of Diverse SubtypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.