Article
Inflammatory role and prognostic value of platelet chemokines in acute coronary syndrome.
Thrombosis and haemostasis - 1 Dec 2014
Blanchet X, Cesarek K, Brandt J, Herwald H, Teupser D, Küchenhoff H, Karshovska E, Mause S F, Siess W, Wasmuth H, Soehnlein O, Koenen R R, Weber C, von Hundelshausen P
Abstract excerpt
Activated platelets and neutrophils exacerbate atherosclerosis. Platelets release the chemokines CXCL4, CXCL4L1 and CCL5, whereas myeloperoxidase (MPO) and azurocidin are neutrophil-derived. We investigated whether plasma levels of these platelet and neutrophil mediators are affected by the acute coronary syndrome (ACS), its medical treatment, concomitant clinical or laboratory parameters, and predictive for the...
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