Article
Maresin 1 induces a novel pro-resolving phenotype in human platelets.
Journal of thrombosis and haemostasis : JTH - 1 Apr 2017
Lannan K L, Spinelli S L, Blumberg N, Phipps R P
Abstract excerpt
Essentials Specialized proresolving mediators (SPMs) promote the resolution of inflammation. This study sought to investigate the effects of SPMs on human platelet function. The SPM, Maresin 1, enhanced hemostatic, but suppressed inflammatory functions of platelets. SPMs uniquely regulate platelet function and may represent a new class of antiplatelet agents. SUMMARY: Background Antiplatelet therapy is a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
