Article
PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function.
PloS one - 1 Jan 2012
De Sutter Johan, Van de Veire Nico R, Struyf Sofie, Philippé Jan, De Buyzere Marc, Van Damme Jo
Abstract excerpt
BACKGROUND: Platelet-derived chemokines are implicated in several aspects of vascular biology. However, for the chemokine platelet factor 4 variant (PF-4var/CXCL4L1), released by platelets during thrombosis and with different properties as compared to PF-4/CXCL4, its role in heart disease is not yet studied. We evaluated the determinants and prognostic value of the platelet-derived chemokines PF-4var, PF-4 and...
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