Article
AliGROOVE--visualization of heterogeneous sequence divergence within multiple sequence alignments and detection of inflated branch support.
BMC bioinformatics - 30 Aug 2014
Kück Patrick, Meid Sandra A, Groß Christian, Wägele Johann W, Misof Bernhard
Abstract excerpt
BACKGROUND: Masking of multiple sequence alignment blocks has become a powerful method to enhance the tree-likeness of the underlying data. However, existing masking approaches are insensitive to heterogeneous sequence divergence which can mislead tree reconstructions. We present AliGROOVE, a new method based on a sliding window and a Monte Carlo resampling approach, that visualizes heterogeneous sequence...
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