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Article

Dietary phosphorus overload aggravates the phenotype of the dystrophin-deficient mdx mouse.

The American journal of pathology - 1 Nov 2014

Wada Eiji, Yoshida Mizuko, Kojima Yoriko, Nonaka Ikuya, Ohashi Kazuya, Nagata Yosuke, Shiozuka Masataka, Date Munehiro, Higashi Tetsuo, Nishino Ichizo, Matsuda Ryoichi

Abstract excerpt

Duchenne muscular dystrophy is a lethal X-linked disease with no effective treatment. Progressive muscle degeneration, increased macrophage infiltration, and ectopic calcification are characteristic features of the mdx mouse, a murine model of Duchenne muscular dystrophy. Because dietary phosphorus/phosphate consumption is increasing and adverse effects of phosphate overloading have been reported in several...

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PMID: 25174878
DOI: 10.1016/j.ajpath.2014.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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