Article
Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain.
The journal of sexual medicine - 1 Dec 2014
Heddini Ulrika, Bohm-Starke Nina, Grönbladh Alfhild, Nyberg Fred, Nilsson Kent W, Johannesson Ulrika
Abstract excerpt
INTRODUCTION: Provoked vestibulodynia (PVD) is a common type of dyspareunia among young women. The patho-physiology remains largely unclear. Women with PVD have general pain hypersensitivity and often report additional pain symptoms. Signs point towards PVD being a chronic pain disorder similar to other syndromes of longstanding pain, including a common comorbidity of anxiety and depression. Polymorphism in the...
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