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Article

Mutation analysis of patients with neurodegenerative disorders using NeuroX array.

Neurobiology of aging - 1 Jan 2015

Ghani Mahdi, Lang Anthony E, Zinman Lorne, Nacmias Benedetta, Sorbi Sandro, Bessi Valentina, Tedde Andrea, Tartaglia Maria Carmela, Surace Ezequiel I, Sato Christine, Moreno Danielle, Xi Zhengrui, Hung Rachel, Nalls Mike A, Singleton Andrew, St George-Hyslop Peter, Rogaeva Ekaterina

Abstract excerpt

Genetic analyses of patients with neurodegenerative disorders have identified multiple genes that need to be investigated for the presence of damaging variants. However, mutation analysis by Sanger sequencing is costly and time consuming. We tested the utility of a recently designed semi-custom genome-wide array (NeuroX; Illumina, Inc) tailored to study neurodegenerative diseases (e.g., mutation screening). We...

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Identifiers

PMID: 25174650
DOI: 10.1016/j.neurobiolaging.2014.07.038
PMCID: PMC4268030

Genes

ABCA7
PSEN1
SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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