Article
Chimerism monitoring after allogeneic hematopoietic stem cell transplantation using quantitative real-time PCR of biallelic insertion/deletion polymorphisms.
The Journal of molecular diagnostics : JMD - 1 Nov 2014
Kim Seon Young, Jeong Moon Hwan, Park Nare, Ra Eunkyoung, Park Hyunwoong, Seo Soo Hyun, Kim Ji Yeon, Seong Moon-Woo, Park Sung Sup
Abstract excerpt
An accurate and sensitive determination of chimerism status is mandatory after allogeneic hematopoietic stem cell transplantation. We evaluated the performance of the AlleleSEQR Chimerism Assay, which is based on quantitative real-time PCR of biallelic indel markers, using 79 recipient-donor pairs. When the informativeness of the screening panel composed of 34 markers was determined using 130 unrelated...
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