Article
Novel alleles at the Kell blood group locus that lead to Kell variant phenotype in the Dutch population.
Transfusion - 1 Feb 2015
Ji Yanli, Veldhuisen Barbera, Ligthart Peter, Haer-Wigman Lonneke, Jongerius John, Boujnan Mohamed, Ait Soussan Aicha, Luo Guangping, Fu Yongshui, van der Schoot C Ellen, de Haas Masja
Abstract excerpt
BACKGROUND: Alloantibodies directed against antigens of the Kell blood group system are clinically significant. In the Netherlands, the KEL1 antigen is determined in all blood donors. In this study, after phenotyping of KEL:1-positive donors, genotyping analysis was conducted in KEL:1,-2 donors to identify possible KEL*02 variant alleles. STUDY DESIGN AND METHODS: A total of 407 donors with the KEL:1,-2 phenotype...
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