Article
Angiotensin converting enzyme intron 16 insertion/deletion genotype is associated with plasma C-reactive protein concentration in uteroplacental dysfunction.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2015
Häupl Thomas, Zimmermann Mathias, Kalus Ulrich, Yürek Salih, Koscielny Jürgen, Hoppe Berthold
Abstract excerpt
INTRODUCTION: Disturbance of the uteroplacental circulation (UPC) and the renin-angiotensin system are involved in the pathogenesis of preeclampsia. In women with history of preeclampsia persistently elevated C-reactive protein (CRP) levels have been described. The angiotensin-converting enzyme (ACE) intron 16 insertion/deletion (I/D) genotype is associated with ACE activity and assumed to be a risk factor for...
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