Article
Antiviral Effects of Artesunate on JC Polyomavirus Replication in COS-7 Cells
26 Aug 2014
Abstract excerpt
The human JC polyomavirus (JCPyV) causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). A growing number of patients with induced or acquired immunosuppression are at risk for infection, and no effective antiviral therapy is presently available. The widely used antimalarial drug artesunate has shown broad antiviral activity in vitro but limited clinical success. The aim of this...
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