Article
Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from northern Kenya.
PloS one - 1 Jan 2014
Odhiambo Collins, Venter Marietjie, Limbaso Konongoi, Swanepoel Robert, Sang Rosemary
Abstract excerpt
Biological phenotypes of tri-segmented arboviruses display characteristics that map to mutation/s in the S, M or L segments of the genome. Plaque variants have been characterized for other viruses displaying varied phenotypes including attenuation in growth and/or pathogenesis. In order to characterize variants of Bunyamwera and Ngari viruses, we isolated individual plaque size variants; small plaque (SP) and...
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