Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VP16 fusion induces the multiple-knockout phenotype of redundant transcriptional repressors partly by Med25-independent mechanisms in Arabidopsis.

FEBS letters - 16 Oct 2014

Fujiwara Sumire, Sakamoto Shingo, Kigoshi Keiko, Suzuki Kaoru, Ohme-Takagi Masaru

Abstract excerpt

Biological functions of only some plant transcriptional repressors are known owing to the lack of knockout lines or unclear phenotypes because of redundancy. Here we show that strong viral activation domain VP16 fusion to the transcriptional repressor FLOWERING LOCUS C reversed its function and caused a stronger phenotype than that of the multiple-knockout line of redundant genes, suggesting the potential of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabidopsis
Share to Arabidopsis Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Plant

Share to Herpes Simplex Virus Protein Vmw65

Share to MADS Domain Proteins

Share to Nuclear Proteins

Share to Recombinant Fusion Proteins

Share to Transcriptional Activation

Source

Identifiers

PMID: 25150167
DOI: 10.1016/j.febslet.2014.08.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VP16 fusion induces the multiple-knockout phenotype of redundant transcriptional repressors partly by Med25-independent mechanisms in Arabidopsis.PMID 25150167Read ↗

Structural and functional analysis of VQ motif-containing proteins in Arabidopsis as interacting proteins of WRKY transcription factors.Semantic proximity Read ↗

Genetic analysis of early flowering mutants in Arabidopsis defines a class of pleiotropic developmental regulator required for expression of the flowering-time switch flowering locus C.Semantic proximity Read ↗

Optimized dCas9 Programmable Transcriptional Activators for PlantsSemantic proximity Read ↗

Induction of phenotypic variation by activation of genes harbouring a maize Spm element in their promoter regions using a TnpA-VP16 fusion protein.Semantic proximity Read ↗

Functional analysis of cauliflower mosaic virus 35S promoter: re-evaluation of the role of subdomains B5, B4 and B2 in promoter activity.Semantic proximity Read ↗

Structure of the VP16 transactivator target in the Mediator.Semantic proximity Read ↗

Defective transcriptional activation by diverse VP16 mutants associated with a common inability to form open promoter complexes.Semantic proximity Read ↗

Uncoupling of the functions of the Arabidopsis VIP1 protein in transient and stable plant genetic transformation by Agrobacterium.Semantic proximity Read ↗

Plant NAC-type transcription factor proteins contain a NARD domain for repression of transcriptional activation.Semantic proximity Read ↗

Characterization of VIP1 activity as a transcriptional regulator in vitro and in planta.Semantic proximity Read ↗

Amino acid substitutions in the herpes simplex virus transactivator VP16 uncouple direct protein-protein interaction and DNA binding from complex assembly and transactivation.Semantic proximity Read ↗

Loss-of-function mutations of retromer large subunit genes suppress the phenotype of an Arabidopsis zig mutant that lacks Qb-SNARE VTI11.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.