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Article

Cryptic genetic variation uncovers evolution of environmentally sensitive parameters in Caenorhabditis vulval development.

Evolution & development - 1 Sept 2014

Grimbert Stéphanie, Braendle Christian

Abstract excerpt

Understanding the robustness of developmental systems requires insights into the sensitivity of underlying molecular and cellular parameters to perturbations, and how such sensitivity evolves. We address these issues using vulval cell fate determination--a reproducible and robust patterning process regulated by a cross-talk of EGF-Ras-MAPK and Delta-Notch pathways. Although the final vulval cell fate pattern is...

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PMID: 25143152
DOI: 10.1111/ede.12091

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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