Article
Bias and evolution of the mutationally accessible phenotypic space in a developmental system.
PLoS genetics - 12 Mar 2010
Braendle Christian, Baer Charles F, Félix Marie-Anne
Abstract excerpt
Genetic and developmental architecture may bias the mutationally available phenotypic spectrum. Although such asymmetries in the introduction of variation may influence possible evolutionary trajectories, we lack quantitative characterization of biases in mutationally inducible phenotypic variation, their genotype-dependence, and their underlying molecular and developmental causes. Here we quantify the...
Topics
- Animals
- Bias
- Biological Evolution
- Caenorhabditis
- Cell Lineage
- Female
- Genetic Variation
- Genotype
- Mutation
- Phenotype
- Signal Transduction
- Vulva