Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cryptic variation in vulva development by cis-regulatory evolution of a HAIRY-binding site.

Nature communications - 1 Jan 2013

Kienle Simone, Sommer Ralf J

Abstract excerpt

Robustness to mutations is a general principle of biological systems that allows for the accumulation of cryptic variation. However, little is known about robustness and cryptic variation in core developmental pathways. Here we show through gonad-ablation screens in natural isolates of Pristionchus pacificus cryptic variation in nematode vulva development. This variation is mainly caused by cis-regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Evolution, Molecular
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nematoda

Share to Proteins

Share to Transgenes

Source

Identifiers

PMID: 23591881
DOI: 10.1038/ncomms2711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cryptic variation in vulva development by cis-regulatory evolution of a HAIRY-binding site.PMID 23591881Read ↗

HAIRY-like transcription factors and the evolution of the nematode vulva equivalence group.Semantic proximity Read ↗

Antagonism of LIN-17/Frizzled and LIN-18/Ryk in nematode vulva induction reveals evolutionary alterations in core developmental pathways.Semantic proximity Read ↗

Cryptic genetic variation uncovers evolution of environmentally sensitive parameters in Caenorhabditis vulval development.Semantic proximity Read ↗

Apoptosis and change of competence limit the size of the vulva equivalence group in Pristionchus pacificus: a genetic analysis.Semantic proximity Read ↗

Evolution of regulatory networks: nematode vulva induction as an example of developmental systems drift.Semantic proximity Read ↗

Role of pleiotropy in the evolution of a cryptic developmental variation in Caenorhabditis elegans.Semantic proximity Read ↗

The nematode Pristionchus pacificus as a model system for integrative studies in evolutionary biology.Semantic proximity Read ↗

The Nuclear Hormone Receptor NHR-40 Acts Downstream of the Sulfatase EUD-1 as Part of a Developmental Plasticity Switch in Pristionchus.Semantic proximity Read ↗

Necessity and Contingency in Developmental Genetic Screens: EGF, Wnt, and Semaphorin Pathways in Vulval Induction of the Nematode Oscheius tipulae.Semantic proximity Read ↗

A Mediator subunit imparts robustness to a polyphenism decision.Semantic proximity Read ↗

Vulva formation in Pristionchus pacificus relies on continuous gonadal induction.Semantic proximity Read ↗

A Developmental Switch Generating Phenotypic Plasticity Is Part of a Conserved Multi-gene Locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.