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Article

Tacrolimus pharmacodynamics and pharmacogenetics along the calcineurin pathway in human lymphocytes.

Clinical chemistry - 1 Oct 2014

Noceti Ofelia M, Woillard Jean-Baptiste, Boumediene Ahmed, Esperón Patricia, Taupin Jean-Luc, Gerona Solange, Valverde Marcelo, Touriño Cristina, Marquet Pierre

Abstract excerpt

BACKGROUND: Although therapeutic drug monitoring has improved the clinical use of immunosuppressive drugs, there is still interpatient variability in efficacy and toxicity that pharmacodynamic monitoring may help to reduce. To select the best biomarkers of tacrolimus pharmacodynamics, we explored...

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Source

Identifiers

PMID: 25142246
DOI: 10.1373/clinchem.2014.223511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25142246-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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