Article
Quantitative effect of natural killer-cell licensing on hepatocellular carcinoma recurrence after curative hepatectomy.
Cancer immunology research - 1 Dec 2014
Tanimine Naoki, Tanaka Yuka, Kobayashi Tsuyoshi, Tashiro Hirotaka, Miki Daiki, Imamura Michio, Aikata Hiroshi, Tanaka Junko, Chayama Kazuaki, Ohdan Hideki
Abstract excerpt
Natural killer (NK) cells have a potential role in immune surveillance of hepatocellular carcinoma (HCC). Self-recognition of human leukocyte antigens (HLA) through killer immunoglobulin-like receptors (KIR) confers competence to NK cells-a process termed "licensing." We investigated the effect of NK-cell licensing on the susceptibility of patients to HCC recurrence. A total of 170 Japanese patients with HCC who...
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