Article
Immunological and molecular correlates of disease recurrence after liver resection for hepatocellular carcinoma.
PloS one - 1 Jan 2012
Cariani Elisabetta, Pilli Massimo, Zerbini Alessandro, Rota Cristina, Olivani Andrea, Pelosi Guido, Schianchi Claudia, Soliani Paolo, Campanini Nicoletta, Silini Enrico Maria, Trenti Tommaso, Ferrari Carlo, Missale Gabriele
Abstract excerpt
The definition of the risk of hepatocellular carcinoma (HCC) recurrence after resection represents a central issue to improve the clinical management of patients. In this study we examined the prognostic relevance of infiltrating immune cell subsets in the tumor (TIL) and in nontumorous (NT) liver (LIL), and the expression of immune-related and lineage-specific mRNAs in HCC and NT liver derived from 42 patients....
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