Article
Adipose stromal vascular fraction improves cardiac function in chronic myocardial infarction through differentiation and paracrine activity.
Cell transplantation - 1 Jan 2012
Mazo Manuel, Cemborain Arantxa, Gavira Juan José, Abizanda Gloria, Araña Miriam, Casado Mayte, Soriano Mario, Hernández Salomón, Moreno Cristina, Ecay Margarita, Albiasu Edurne, Belzunce Miriam, Orbe Josune, Páramo José Antonio, Merino Juana, Peñuelas Iván, Verdugo José Manuel García, Pelacho Beatriz, Prosper Felipe
Abstract excerpt
Fresh adipose-derived cells have been shown to be effective in the treatment of acute myocardial infarction (MI), but their role in the chronic setting is unknown. We sought to determine the long-term effect of the adipose derived-stromal vascular fraction (SVF) cell transplantation in a rat model of chronic MI. MI was induced in 82 rats by permanent coronary artery ligation and 5 weeks later rats were allocated...
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