Article
Transplantation of Immortalized CD34+ and CD34- Adipose-Derived Stem Cells Improve Cardiac Function and Mitigate Systemic Pro-Inflammatory Responses.
PloS one - 1 Jan 2016
Kim Jong-Ho, Choi Seung-Cheol, Park Chi-Yeon, Park Jae-Hyoung, Choi Ji-Hyun, Joo Hyung-Joon, Hong Soon-Jun, Lim Do-Sun
Abstract excerpt
Adipose-derived stem cells (ADSCs) have the potential to differentiate into various cell lineages and they are easily obtainable from patients, which makes them a promising candidate for cell therapy. However, a drawback is their limited life span during in vitro culture. Therefore, hTERT-immortalized CD34+ and CD34- mouse ADSC lines (mADSCshTERT) tagged with GFP were established. We evaluated the proliferation...
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