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Article

Impact of hepcidin antimicrobial peptide on iron overload in tuberculosis patients.

Scandinavian journal of infectious diseases - 1 Oct 2014

Javaheri-Kermani Mina, Farazmandfar Touraj, Ajami Abolghasem, Yazdani Yaghoub

Abstract excerpt

BACKGROUND: Iron acquisition is essential for the growth of Mycobacterium tuberculosis. Hepcidin is known as an antimicrobial peptide and a component of the innate immune response. Hepcidin inhibits M. tuberculosis growth in vitro. In this study, we decided to identify -582A> G variants of the HAMP promoter in patients with tuberculosis (TB) and investigate its effect on serum iron, ferritin, and hepcidin levels....

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Share to Enzyme-Linked Immunosorbent Assay
Share to Ferritins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Point Mutation

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 25134646
DOI: 10.3109/00365548.2014.929736

Genes

HAMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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