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Article

DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease.

Respiratory research - 20 Aug 2014

Lee Jin Hwa, McDonald Merry-Lynn N, Cho Michael H, Wan Emily S, Castaldi Peter J, Hunninghake Gary M, Marchetti Nathaniel, Lynch David A, Crapo James D, Lomas David A, Coxson Harvey O, Bakke Per S, Silverman Edwin K, Hersh Craig P

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation, causing air trapping and lung hyperinflation. Hyperinflation leads to reduced exercise tolerance and poor quality of life in COPD patients. Total lung capacity (TLC) is an indicator of hyperinflation particularly in subjects with moderate-to-severe airflow obstruction. The aim of our study was to identify...

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Identifiers

PMID: 25134640
DOI: 10.1186/s12931-014-0097-y
PMCID: PMC4169636

Genes

DNAH5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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