Article
Unclassified renal cell carcinoma: a clinicopathological, comparative genomic hybridization, and whole-genome exon sequencing study.
International journal of clinical and experimental pathology - 1 Jan 2014
Hu Zhen-Yan, Pang Li-Juan, Qi Yan, Kang Xue-Ling, Hu Jian-Ming, Wang Lianghai, Liu Kun-Peng, Ren Yuan, Cui Mei, Song Li-Li, Li Hong-An, Zou Hong, Li Feng
Abstract excerpt
Unclassified renal cell carcinoma (URCC) is a rare variant of RCC, accounting for only 3-5% of all cases. Studies on the molecular genetics of URCC are limited, and hence, we report on 2 cases of URCC analyzed using comparative genome hybridization (CGH) and the genome-wide human exon GeneChip technique to identify the genomic alterations of URCC. Both URCC patients (mean age, 72 years) presented at an advanced...
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