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Article

The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.

PloS one - 1 Jan 2014

Kaya Gizem A, Coşkun Ayse N, Yılmaz Vuslat, Oflazer Piraye, Gülsen-Parman Yeşim, Aysal Fikret, Disci Rian, Direskeneli Haner, Marx Alexander, Deymeer Feza, Saruhan-Direskeneli Güher

Abstract excerpt

A functional single nucleotide polymorphism (SNP) of the PTPN22 gene encoding a protein tyrosine phosphatase has been associated with autoimmune disorders including myasthenia gravis (MG). As the PTPN22 R620W polymorphism has a wide variation of allele frequencies among different populations, this polymorphism was investigated in MG in Turkey. An emphasis is put on MG subgroups according to autoantibody (Abs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25119822
DOI: 10.1371/journal.pone.0104760
PMCID: PMC4132102

Genes

PTPN22

Variants

rs2476601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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