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Article

Aging and genome maintenance: lessons from the mouse?

Science (New York, N.Y.) - 28 Feb 2003

Hasty Paul, Campisi Judith, Hoeijmakers Jan, van Steeg Harry, Vijg Jan

Abstract excerpt

Recent progress in the science of aging is driven largely by the use of model systems, ranging from yeast and nematodes to mice. These models have revealed conservation in genetic pathways that balance energy production and its damaging by-products with pathways that preserve somatic maintenance....

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PMID: 12610296
DOI: 10.1126/science.1079161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12610296-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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