Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essentiality of succinate dehydrogenase in Mycobacterium smegmatis and its role in the generation of the membrane potential under hypoxia.

mBio - 12 Aug 2014

Pecsi Ildiko, Hards Kiel, Ekanayaka Nandula, Berney Michael, Hartman Travis, Jacobs William R, Cook Gregory M

Abstract excerpt

UNLABELLED: Succinate:quinone oxidoreductase (Sdh) is a membrane-bound complex that couples the oxidation of succinate to fumarate in the cytoplasm to the reduction of quinone to quinol in the membrane. Mycobacterial species harbor genes for two putative sdh operons, but the individual roles of these two operons are unknown. In this communication, we show that Mycobacterium smegmatis mc(2)155 expresses two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fumarates
Share to Membrane Potentials

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium smegmatis

Share to Operon

Share to Oxygen

Share to Oxygen Consumption

Share to Succinate Dehydrogenase

Share to Succinates

Source

Open in PubMed Open full text

Identifiers

PMID: 25118234
DOI: 10.1128/mBio.01093-14
PMCID: PMC4145680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essentiality of succinate dehydrogenase in Mycobacterium smegmatis and its role in the generation of the membrane potential under hypoxia.PMID 25118234Read ↗

Impaired succinate oxidation prevents growth and influences drug susceptibility in <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Succinate dehydrogenase deficiency in human.Semantic proximity Read ↗

Succinate dehydrogenase and human diseases: new insights into a well-known enzyme.Semantic proximity Read ↗

Deciphering functional redundancy and energetics of malate oxidation in mycobacteriaSemantic proximity Read ↗

Succinate dehydrogenase: the complex roles of a simple enzyme.Semantic proximity Read ↗

Molecular genetics of succinate:quinone oxidoreductase in eukaryotes.Semantic proximity Read ↗

Succinate Dehydrogenase, Succinate, and Superoxides: A Genetic, Epigenetic, Metabolic, Environmental Explosive CrossroadSemantic proximity Read ↗

Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complexSemantic proximity Read ↗

Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate.Semantic proximity Read ↗

The Saccharomyces cerevisiae succinate dehydrogenase anchor subunit, Sdh4p: mutations at the C-terminal lys-132 perturb the hydrophobic domain.Semantic proximity Read ↗

Two membrane anchors of Wolinella succinogenes hydrogenase and their function in fumarate and polysulfide respirationSemantic proximity Read ↗

Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p paralogs results in catalytically active succinate dehydrogenase isoenzymes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.