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Article

VPS35 and DNAJC13 disease-causing variants in essential tremor.

European journal of human genetics : EJHG - 1 Jun 2015

Rajput Alex, Ross Jay P, Bernales Cecily Q, Rayaprolu Sruti, Soto-Ortolaza Alexandra I, Ross Owen A, van Gerpen Jay, Uitti Ryan J, Wszolek Zbigniew K, Rajput Ali H, Vilariño-Güell Carles

Abstract excerpt

Exome-sequencing analyses have identified vacuolar protein sorting 35 homolog (VPS35) and DnaJ (Hsp40) homolog, subfamily C, member 13 (DNAJC13) harboring disease-causing variants for Parkinson disease (PD). Owing to the suggested clinical, pathological and genetic overlap between PD and essential tremor (ET) we assessed the presence of two VPS35 and DNAJC13 disease-causing variants in ET patients. TaqMan probes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25118025
DOI: 10.1038/ejhg.2014.164
PMCID: PMC4795043

Genes

DNAJC13
VPS35

Variants

rs188286943
rs387907571
rs188286943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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