Article
Solving the problem of comparing whole bacterial genomes across different sequencing platforms.
PloS one - 1 Jan 2014
Kaas Rolf S, Leekitcharoenphon Pimlapas, Aarestrup Frank M, Lund Ole
Abstract excerpt
Whole genome sequencing (WGS) shows great potential for real-time monitoring and identification of infectious disease outbreaks. However, rapid and reliable comparison of data generated in multiple laboratories and using multiple technologies is essential. So far studies have focused on using one technology because each technology has a systematic bias making integration of data generated from different platforms...
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