Article
Oxidative stress-mediated (sex-specific) loss of protection against type-2 diabetes by macrophage migration inhibitory factor (MIF)-173G/C polymorphism.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2015
Coban Neslihan, Onat Altan, Yildirim Ozlem, Can Gunay, Erginel-Unaltuna Nihan
Abstract excerpt
BACKGROUND: The archetypical yet atypical cytokine macrophage migration inhibitory factor (MIF) fulfills pleiotropic immune functions in inflammatory diseases. Evidence emerging from both expression and functional studies implicates MIF in various aspects of cardiovascular diseases. We aimed to determine the covariates of MIF-173G/C polymorphism and its influence on type-2 diabetes risk in a sample representative...
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