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Article

A Critical Kinase Cascade In Neurological Disorders: Pi3K, Akt and Mtor

7 Nov 2012

Abstract excerpt

Neurodegenerative disorders lead to disability and death in a significant proportion of the world's population. However, many disorders of the nervous system remain with limited effective treatments. Kinase pathways in the nervous system that involve phosphoinositide 3-kinase (PI 3-K), protein kinase B (Akt), and the mammalian target of rapamycin (mTOR) offer exciting prospects for the understanding of...

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PMID: 23144589
DOI: 10.2217/fnl.12.72

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