Article
Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions.
BMC genomics - 5 Aug 2014
Dutilh Bas E, Thompson Cristiane C, Vicente Ana C P, Marin Michel A, Lee Clarence, Silva Genivaldo G Z, Schmieder Robert, Andrade Bruno G N, Chimetto Luciane, Cuevas Daniel, Garza Daniel R, Okeke Iruka N, Aboderin Aaron Oladipo, Spangler Jessica, Ross Tristen, Dinsdale Elizabeth A, Thompson Fabiano L, Harkins Timothy T, Edwards Robert A
Abstract excerpt
BACKGROUND: Vibrio cholerae is a globally dispersed pathogen that has evolved with humans for centuries, but also includes non-pathogenic environmental strains. Here, we identify the genomic variability underlying this remarkable persistence across the three major niche dimensions space, time, and habitat. RESULTS: Taking an innovative approach of genome-wide association applicable to microbial genomes (GWAS-M),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.