Article
Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.
PloS one - 1 Jan 2014
Sabater-Lleal Maria, Mälarstig Anders, Folkersen Lasse, Soler Artigas María, Baldassarre Damiano, Kavousi Maryam, Almgren Peter, Veglia Fabrizio, Brusselle Guy, Hofman Albert, Engström Gunnar, Franco Oscar H, Melander Olle, Paulsson-Berne Gabrielle, Watkins Hugh, Eriksson Per, Humphries Steve E, Tremoli Elena, de Faire Ulf, Tobin Martin D, Hamsten Anders
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung function...
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