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Acetylsalicylic acid, aging and coronary artery disease are associated with ABCA1 DNA methylation in men

29 Jul 2014

Abstract excerpt

BACKGROUND: Previous studies have suggested that DNA methylation contributes to coronary artery disease (CAD) risk variability. DNA hypermethylation at the ATP-binding cassette transporter A1 (ABCA1) gene, an important modulator of high-density lipoprotein cholesterol and reverse cholesterol transport, has been previously associated with plasma lipid levels, aging and CAD, but the association with CAD has yet to...

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PMID: 25093045
DOI: 10.1186/1868-7083-6-14

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