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ABCA1 and ABCG1 DNA methylation in epicardial adipose tissue of patients with coronary artery disease

27 Nov 2021

Abstract excerpt

BACKGROUND: Recent studies have focused on the potential role of epicardial adipose tissue (EAT) in the development of coronary artery disease (CAD). ABCA1 and ABCG1 transporters regulate cell cholesterol content and reverse cholesterol transport. We aimed to determine whether DNA methylation and mRNA levels of the ABCA1 and ABCG1 genes in EAT and subcutaneous adipose tissue (SAT) were associated with CAD....

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PMID: 34837967
DOI: 10.1186/s12872-021-02379-7

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