Article
A Conserved Apicomplexan Microneme Protein Contributes to Toxoplasma gondii Invasion and Virulence
5 Aug 2014
Abstract excerpt
The obligate intracellular parasite Toxoplasma gondii critically relies on host cell invasion during infection. Proteins secreted from the apical micronemes are central components for host cell recognition, invasion, egress, and virulence. Although previous work established that the sporozoite protein with an altered thrombospondin repeat (SPATR) is a micronemal protein conserved in other apicomplexan parasites,...
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