Article
A thrombospondin structural repeat containing rhoptry protein fromPlasmodium falciparummediates erythrocyte invasion
6 Feb 2013
Abstract excerpt
Host cell invasion by Plasmodium falciparum requires multiple molecular interactions between host receptors and parasite ligands. A family of parasite proteins, which contain the conserved thrombospondin structural repeat motif (TSR), has been implicated in receptor binding during invasion. In this study we have characterized the functional role of a TSR containing blood stage protein referred to as P. falciparum...
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