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Article

A validated miRNA profile predicts response to therapy in esophageal adenocarcinoma

4 Aug 2014

Abstract excerpt

BACKGROUND: In the current study we present a validated miRNA signature to predict pathologic complete response (pCR) to neoadjuvant chemoradiation in esophageal adenocarcinoma. METHODS: Three patient cohorts (discovery, n = 10; model, n = 43; and validation, n = 65) with locally advanced esophageal adenocarcinoma were analyzed. In the discovery cohort 754 miRNAs were examined in pretreatment tumor biopsy...

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PMID: 25091571
DOI: 10.1002/cncr.28911

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