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Intracellular Bacteria in the Pathogenesis of Escherichia coli Urinary Tract Infection in Children

4 Aug 2014

Abstract excerpt

BACKGROUND: Uropathogenic Escherichia coli (UPEC) is the most common agent of urinary tract infection (UTI). The classic model of pathogenesis proposes the ascent of UPEC by the urethra and external adherence to the urothelium. Recently, the ability of UPEC to invade urothelial cells and to form intracellular bacterial communities (IBCs) has been described. METHODS: The objective of the present study was to...

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PMID: 25091303
DOI: 10.1093/cid/ciu634

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