<i>Escherichia coli</i> from Urine of Female Patients with Urinary Tract Infections Is Competent for Intracellular Bacterial Community Formation

Abstract excerpt

Nearly 50% of women experience at least one urinary tract infection (UTI) in their lifetime. Studies with mice have revealed that uropathogenic Escherichia coli (UPEC) isolates invade superficial umbrella cells that line the bladder, allowing them to find a safe haven and subvert clearance by innate host responses. Rapid intracellular replication results in the formation of distinctive intracellular bacterial...

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