Article
High Quality RNA in Semen and Sperm: Isolation, Analysis and Potential Application in Clinical Testing
1 Aug 2014
Abstract excerpt
PURPOSE: Male infertility is a complex health condition. To our knowledge there are no molecular biomarkers of male infertility. Sperm RNA is a potential biomarker for detecting sperm abnormalities and viability at infertility clinics. However, RNA use is hindered by its inconsistent quantity, quality, multiple cell types in semen and condensed sperm structure. MATERIALS AND METHODS: We tested the usefulness of...
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