Article
Discovery and characterization of miRNA during cellular senescence in bone marrow-derived human mesenchymal stem cells.
Experimental gerontology - 1 Oct 2014
Yoo Jung Ki, Kim Chang-Hyun, Jung Ho Yong, Lee Dong Ryul, Kim Jin Kyeoung
Abstract excerpt
Cellular senescence is an irreversible cell cycle arrest in which specific mRNAs and miRNAs are involved in senescence progression. miRNAs interact with specific mRNAs to regulate various cellular mechanisms, including metabolism, proliferation, apoptosis, senescence and differentiation. In this study, we identify and characterize miRNAs during cellular senescence in mesenchymal stem cells (MSCs). Using...
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