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Article

MiR-483 induces senescence of human adipose-derived mesenchymal stem cells through IGF1 inhibition.

Aging - 15 Aug 2020

Shen Junyan, Zhu Xiaoqi, Liu Hailiang

Abstract excerpt

Human adipose-derived mesenchymal stem cells (hADSCs) are an ideal source of seed cells for regenerative applications and tissue engineering. However, long-term in vitro culture of hADSCs reduces their quantity and quality, which lessens their value in research and clinical applications. The molecular mechanisms underlying this biological process are poorly defined. Recently identified microRNAs (miRNAs) have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32805717
DOI: 10.18632/aging.103818
PMCID: PMC7467354

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